Article Type : Case Report
Authors : Degirmenci H, Bakirci EM, Co?gun MS, Olmez H and Dogan MO
Keywords : Right sinus valsalva; Circumflex coronary artery; Frequent; Myocardial infarction; Coronary angiography; Early intervention
Circumflex coronary
artery originating from the right sinus valsalva is a common coronary anomaly
that rarely causes symptoms. However, acute myocardial infarction and sudden
death may occur. In this case, he presented with acute inferoposterior
myocardial infarction. These anomalies are usually diagnosed by coronary
angiography. Knowing this anomaly is important for early intervention to the
lesion.
Congenital coronary artery anomalies can lead to a
wide range of clinical pictures from acute coronary syndrome to sudden death
[1]. However, it is mostly asymptomatic. Coronary artery anomalies are detected
in 0.6-1.5% of the patients undergoing coronary angiography [1]. The diagnosis
of coronary artery anomalies is usually made by coronary angiography [2]. The
circumflex coronary artery originating from the right sinus valsalva has no
apparent clinical significance [3]. However, it is important to be taken into
consideration in patients presenting with acute coronary syndrome, in order to
avoid loss of time and early intervention. In this article, we present a
circumflex coronary artery lesion presenting with acute inferoposterior
myocardial infarction and originating from the right sinus valsalva.
A 39-year-old male patient was admitted to the emergency clinic with a pressing chest pain that started 1 hour ago. There were no risk factors for coronary artery disease. His blood pressure was 115/75 mmHg, heart rate was 107/min, and respiratory rate was 12/min. Heart sounds were normal on listening. There was normal sinus rhythm on electrocardiography. In addition, there was ST segment elevation in D2, D3 and a VF, V5 and V6 on electrocardiography (Figure 1).
Figure 1: There
is an appearance of acute inferoposterior myocardial infarction on
electrocardiography.
In the emergency clinic, the patient was given 300 mg ASA and 180 mg ticagrelor. In addition, 70 IU/kg intravenous heparin was administered. The patient was evaluated by the cardiology clinic and was taken to the emergency coronary angiography unit with the diagnosis of acute inferposterior myocardial infarction. Coronary angiography was performed with a right Judkins 4 cm curve catheter with a radical approach, and the right coronary artery was evaluated as normal. The left anterior descending coronary artery was evaluated as normal in the left imaging performed with a left 3.5 cm curve judkins catheter, but the circumflex coronary artery was not observed (Figure 2).
Figure 2: There
is no circumflex coronary artery in the left coronary artery imaging.
Since the coronary artery could not be seen on left imaging, imaging was performed on the circumflex coronary artery in the right sinus valsalva in terms of possible coronary artery anomaly. Imaging revealed that the circumflex coronary artery originating from the right sinus valsalva was totally occluded (Figure 3).
Figure 3: Circumflex
coronary artery originating from the right sinus valsalva is seen to be totally
occluded.
Subsequently, the lesion was passed with a 0.014 inch guide wire and predilation was performed with 2.0 × 20 and 2.5 × 20 mm semi-compliant balloons. Afterwards, a 2.75 × 38 mm drug eluting stent was implanted in the circumflex coronary artery with 95% lesions. Subsequently, post-dilatation was performed with a 3.5 × 15 noncompliant balloon. Complete patency was achieved in the coronary artery originating from the right sinus valsalva (Figure 4).
Figure 4: It is seen that the
circumflex coronary artery originating from the right sinus valsalva is fully
opened after the procedure.
Sirkumflex coronary
artery relative to the right sinus valsalva is a common anatomic variation [4].
This anomaly was first described by Antopol and Kugel in 1933, and its
prevalence in angiographic series is 0.4-0.8% [2]. This variation was found to
be at high risk of atherosclerosis in some studies [5]. In patients undergoing
mitral valve surgery, the circumflex originating from the right sinus valsalva
has been found to be associated with myocardial infarction [6]. This anomaly is
usually asymptomatic and may present with acute myocardial infarction or sudden
death [7]. In our case, it was presented with acute myocardial infarction. This
presentation may be due to the increased risk of atherosclerosis, as we
mentioned before. Conventional coronary angiography is very important in the
diagnosis of coronary artery anomalies. We also diagnosed this anomaly by
coronary angiography. In this anomaly, the right guiding catheter is extremely
useful in intervening the lesion [8].
In conclusion,
circumflex coronary artery anomaly originating from the right sinus valsalva is
rarely symptomatic. This anomaly is common and may present with myocardial
infarction. For this reason, it should be considered in order not to waste time
and to intervene in the lesion early.
The author has no
relevant affiliations or financial involvement with a financial interest in or financial with the subject matter or materials discussed in
the manuscript.
There
is no conflict of interest.