Article Type : Clinical Image
Authors : Gurav R, Sundaram S, Nadavinamani Shivanand R, Singh B and Muktevi S
Tuberculosis is a multisystem disease
with numerous presentations and manifestations. It is the most common cause of
infectious disease-related mortality worldwide. Extra-pulmonary TB incidence is
20.8%. Bone and joint involvement are the third most common, comprising 10-15%
of cases. Tuberculous spondylitis is the most common manifestation of bone
& joint involvement, accounting for approximately 40-50% of these cases.
Sacroiliac joint (SIJ) involvement
has been reported in up to 9.7 percent of patients with bone & joint
skeletal tuberculosis. Lack of awareness of this uncommon infection often leads
to diagnostic delay and increased morbidity. Here we are presenting a rare case
of SIJ skeletal tuberculosis. A 46 yrs. male presented with a history of
intermittent fever, anorexia, malaise and a pus discharging wound (sinus) on
the left Lower abdomen since 1 & ½ years.
On examination he was found to be
febrile and he had continuous discharging sinus of 3 cm. In left iliac region. His
spine and neurology examination was found to be normal. His abdomen examination
revealed a diffuse tenderness in Left lower region. Provisional diagnosis of
psoas abscess (cold abscess) with draining sinus was considered.
His CBC was normal, CRP was elevated
78mg/L and ESR 53mm at 1hr. His Xray & MRI of spine was found to be normal.
Surgical drainage & biopsy of the Sacroiliac joint
lesion was planned.
Sacroiliac joint was approached under image intensifier from lateral trans-gluteal approach. The gluteus maximus was split longitudinally to reach the lateral sacroiliac joint & a rectangle cortical window was achieved with the help of an osteotome. Pus was drained, joint curetted and a biopsy was taken. The left iliac region sinus was explored by General surgeon after elliptical excision of sinus. The track of sinus was near to ileacus muscle and anterior to sacroiliac joint. The pus was drained & biopsy taken from sinus too. Wounds were closed over drain. Intraoperative and postoperative period was uneventful and patient remained stable.
Histopathology
Biopsy revealed caseous material
surrounded by clusters of epitheloid cells & few multinucleated giant cells
with moderate lymphocytic infiltration suggestive of tubercular etiology. TB
PCR was positive from biopsy. Patient was started on antitubercular treatment.
He tolerated the antitubercular treatment and his general condition improved
with significant healing of his sinus in two months.
Discussion
Isolated sacroiliac involvement is
very rare. It usually presents as vague back pain. Plain radiographs are often
inconclusive in early disease. Due to rarity of lesion, vague symptoms and
non-conclusive X-rays the diagnosis is further delayed. Sacroiliac tuberculosis
must be kept as a differential in all refractory low back pain particularly in
endemic areas. MRI is very helpful in early diagnosis of disease. Tuberculosis
of bone usually follows primary infection. The mycobacteria spread
haematogenously at the time of the primary infection or, later, from a dormant
primary site or from another extra-osseous secondary focus.
In our patient pelvic radiographs,
bone scans and CT scan showed a localized lesion at the left sacroiliac joint.
These methods of investigation give satisfactory results in the majority of
patients with inflammatory disease, although they do not have the sensitivity
to differentiate pyogenic from granulomatous sacroiliitis. Therefore an open
biopsy is required with drainage of sinus and to confirm the diagnosis with the
help of histological and microbiological findings.
In addition, significant clinical
improvement after antitubercular treatment further supported the diagnosis of
sacroiliac joint tuberculosis in our patient.